ADS032 ADS032 is a dual inhibitor of NLRP1 and NLRP3 that rapidly, reversibly and stably inhibits inflammasome formation and reduces NLPR1 and NLRP3 activation of human-derived macrophages and bronchial epithelial cells to secrete and mature IL-1? and TNF-?, and minimizes NLRP3-induced ASC speck development.the SB120 does An impressive job of handl